Research & Development
Tesis Biosciences developing approach to differentiate mTBI from PTSD
The firm is developing a high-throughput genomics approach to differentiate mild traumatic brain injury from post-traumatic stress disorder.
December 9, 2022
BrainBox secures $3.5M NINDS grant
The company will use the funding to develop a test system for mild traumatic brain injury in elderly patients. In addition, it will collaborate with the Virginia Tech Carilion School of Medicine in Roanoke, VA, on a trial called the HeadSmart Geriatrics Study. The test will integrate blood biomarkers and functional tests.
March 20, 2022
NanoDx inks deal with IBM, seeks EUA for COVID-19 test
Under the deal, NanoDx will get use of IBM's complementary metal oxide semiconductor (CMOS)-compatible nanoscale sensors to enhance and expand rapid testing for conditions such as sepsis, stroke, traumatic brain injury, and COVID-19.
July 13, 2021
Abbott wins FDA nod for blood test to diagnose concussion
The test identifies and measures specific proteins that are present in the blood after a traumatic brain injury. Clinicians can use the diagnostic to confirm or rule out the need for CT scans, according to Abbott.
January 10, 2021
Evidence builds for neurofilament light blood test in brain injury patients
The authors of the study, which was funded by the NIH and the U.S. Department of Defense (DOD), see the results as an encouraging step for the development of serum NfL as a noninvasive biomarker and potential alternative to NfL in cerebral spinal fluid (CSF) for the assessment of TBIs. Researchers published prospective experience with two cohorts: 45 hockey players with acute concussion treated in Sweden, and 230 TBI patients and healthy controls at the NIH's Clinical Center, a research hospital in Bethesda, MD.
July 14, 2020
Blood samples, PET imaging link brain injuries to chronic encephalopathy
Researchers observed elevated levels of tau tangles and a certain blood chemical associated with traumatic brain injury (TBI), both of which could indicate current or future acute brain degeneration and possible progression to CTE as a result of brain injury from an improvised explosive device (IED).
February 26, 2020
Genetic causes identified for three rare diseases
Researchers in study validate test to identify newborns with homocystinuria, a rare inherited disease
FDA reissues EUA for Janssen COVID-19 vaccine, includes warning about risks of myocarditis, pericarditis
National hepatitis C elimination program represents an historic opportunity, according to White House
Netherlands researchers combine CRISPR, bioluminescence in proof-of-concept infectious disease test
Duke University researchers discover biomarkers may identify early pancreatic cancer risk
AI market on the rise | Pathology makeover wanted | A closer look at traumatic brain injury
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October 14, 2019
Pathology study challenges conventional wisdom on brain injury
The prospective Traumatic Head Injury Neuroimaging Classification (THINC) study was funded by the U.S. Department of Defense and the National Institute of Neurological Disorders and Stroke (NINDS).
October 14, 2019
Blood test for detecting subconcussive injury on the horizon
A group from Orlando Health, a not-for-profit healthcare organization in central Florida, and other U.S. institutions has made strides in developing a standard blood test that can spot concussive and subconcussive injuries, the latter of which are asymptomatic but cause brain damage over time with repeated injuries.
August 25, 2019
Inflammatory biomarker blood tests play the field in concussion
In the prospective study, 857 male high school and college-aged players underwent blood testing at baseline for a variety of inflammatory biomarkers. IL-6 and IL-1RA were significantly elevated in a cohort of 41 players with concussion six hours after the injury, compared with preinjury and postinjury levels, and also compared with matched controls, according to senior author Timothy Meier, PhD, an assistant professor of neurosurgery at the Medical College of Wisconsin, and colleagues.
July 3, 2019
BrainBox concussion test wins breakthrough status
The company's BrainBox TBI product includes a panel test for blood protein biomarkers that could be indicators of traumatic brain injury (TBI), including glial fibrillary acidic protein, neuron-specific enolase, and neurogranin. BrainBox TBI evaluates neurological features to make an overall assessment in a single score for mild TBI, or concussion.
June 6, 2019
Abbott, DOD advance research on concussion blood test
Abbott, the DOD, and the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) network will evaluate the point-of-care blood test for Abbott's i-Stat Alinity system. The system performs a number of blood tests within minutes at a patient's bedside, using only two to three drops of blood. i-Stat is already in use within the military as well as at hospitals globally.
April 30, 2019
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