Research & Development
Sepsis: Page 4
Flu shots may protect against severe COVID-19
The annual flu shot may reduce the risks of stroke, sepsis, and deep vein thrombosis (DVT) in patients with COVID-19. Also, those who received influenza vaccines were significantly less likely to visit emergency departments and be admitted to intensive care units, according to the findings.
August 3, 2021
Ortho launches IL-6 reagent pack
Conditions that can be targeted by the test include autoimmune disorders, sepsis, severe respiratory infections from COVID-19, and community-acquired pneumonia in critically ill patients.
July 22, 2021
NanoDx inks deal with IBM, seeks EUA for COVID-19 test
Under the deal, NanoDx will get use of IBM's complementary metal oxide semiconductor (CMOS)-compatible nanoscale sensors to enhance and expand rapid testing for conditions such as sepsis, stroke, traumatic brain injury, and COVID-19.
July 13, 2021
CMS continues NTAP for T2's bacteria panel in FY 2021
The extension allows U.S. hospitals treating sepsis patients who are covered by Medicare to remain eligible for an NTAP of $97.50 for the T2Bacteria panel. This payment covers 65% of the average cost of the test panel, which detects pathogens that cause sepsis, for eligible patients, according to the company.
September 22, 2020
Sphingotec launches point-of-care biomarker test for sepsis, COVID-19
Bio-ADM blood levels reflect in real time the functional status of the endothelium. Endothelial function failure precedes edema and the life-threatening blood pressure drop that causes shock and multiorgan failure -- for instance in sepsis patients. Recent data also show that elevated bio-ADM blood levels identify patients in the general intensive care unit (ICU) patient population who require immediate life-saving therapeutic interventions. Monitoring endothelial function can also help in identifying COVID-19 disease progression.
July 23, 2020
Immunexpress to develop sepsis test with BARDA grant
The grant from BARDA, which is an office of the U.S. Department of Health and Human Services, will cover development and filing for a U.S. Food and Drug Administration emergency use authorization for the host response sepsis test SeptiCyte Rapid.
June 18, 2020
Procalcitonin test signals infection in heart attack patients
As an important marker for inflammation in the body, a blood test for PCT is useful for systemic bacterial infections and sepsis. But its value for detecting infection in patients with acute ST-elevation myocardial infarction (STEMI) -- an area of unmet need -- has been unclear. One key question is whether it is specific enough for infection, or whether levels would increase due to cardiac injury -- a limitation of other inflammatory biomarkers such as C-reactive protein (CRP) and white blood cell counts.
June 15, 2020
Beckman Coulter debuts new tabletop hematology analyzer
Targeted at mid-volume laboratories, DxH 690T provides similar functionality as Beckman Coulter's flagship DxH 900 large-volume hematology analyzer, but in a tabletop configuration, according to the vendor. The DxH 690T supports Beckman Coulter's Early Sepsis Indicator test for identifying adult patients who either have sepsis or have an increased risk of developing the life-threatening condition, as part of a standard complete blood count (SBC) with differential.
May 19, 2020
Cytovale tests sepsis diagnostic in COVID-19 patients
BARDA, which is an office within the U.S. Department of Health and Human Services, is contributing $3.83 million out of the $5.9 million needed for validation and advanced research of Cytovale's rapid sepsis diagnostic system, including the COVID-19 pilot study, and Cytovale is footing the bill for the remainder.
April 22, 2020
Immunexpress gets CE Mark for sepsis test
The test combines the company's SeptiCyte technology with Biocartis' Idylla platform and provides results in an hour. The reverse transcription polymerase chain reaction (RT-PCR) test is a gene expression assay that quantifies the relative expression levels of host response genes isolated from whole blood collected in the PAXgene blood RNA tube, according to the company.
March 26, 2020
Pathologists advance understanding of deadly female genital tract infections
Group A strep is typically found in the mouth, but it can also infect other mucosal areas of the body, with deadly results. The researchers noted that GAS surface proteins cause an estimated 700 million human infections annually around the world, including 15 million in the U.S. GAS is at the root of puerperal sepsis (also known as childbed fever), which is the leading cause of maternal deaths, and it causes necrotizing myometritis (inflammation of the uterine myometrium) as well as severe infections in newborns.
March 18, 2020
C-reactive protein test falls flat in newborns with suspected sepsis
The systematic review and meta-analysis evaluated the accuracy of CRP for determining the risk of late-onset infection in hospitalized neonatal patients, most of whom were preterm and had low birthweight. In the studies included in the analysis, CRP was compared with microbiological blood culture results as a reference standard.
February 11, 2020
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