Ovarian Cancer: Page 2

Illumina, Merck partner on HRD test
By LabPulse.com staff writers
Illumina will leverage its TruSight oncology (TSO) 500 content to develop a new HRD CDx test for the European Union and the U.K. to aid in the identification of ovarian cancer patients with positive HRD status who are eligible for treatment with Lynparza, an (ADP-ribose) polymerase inhibitor.
September 7, 2021
2019 11 15 22 54 6305 Business Hands 400
FDA clears Foundation's FoundationOne Liquid CDx
By LabPulse.com staff writers
The new indications are for alpelisib (Piqray) for advanced or metastatic breast cancer; rucaparib (Rubraca) for advanced ovarian cancer; and alectinib (Alecensa) for metastatic NSCLC.
October 28, 2020
2020 06 01 18 51 2022 Cancer Lung 400
Medicare to pay for Myriad's BRCA testing in prostate cancer patients
By LabPulse.com staff writers
Lynparza is approved for patients with deleterious or suspected deleterious germline or somatic homologous recombination repair gene-mutated metastatic castration-resistant prostate cancer. BRCA testing in prostate cancer has been gaining steam with the approval of new indications for Lynparza (Merck/AstraZeneca) and other PARP inhibitors for this tumor type, building on the original approved use for treatment of ovarian cancer.
July 30, 2020
2020 04 30 21 13 0442 Medicare Puzzle 400
Healthy Nevada Project: Community genetic testing needed
By Kate Madden Yee
The study, conducted by researchers from the Healthy Nevada Project, focused on identifying carriers of hereditary breast and ovarian cancer, Lynch syndrome, and familial hypercholesterolemia.
July 28, 2020
2020 07 28 17 56 2985 2020 07 27 Community Screening 400
Week in Review: Flurry of FDA actions | Google Health's pathology AI demo | Tool for typing serous ovarian cancer
By Emily Hayes
Dear LabPulse Member,
June 18, 2020
Molecular genotyping shines light on serous ovarian cancer
By Emily Hayes
High-grade serous ovarian cancer is the most malignant form of ovarian cancer, causing up to 70% of ovarian cancer deaths. The new study validated a new classifier tool called the predictor of high-grade serous ovarian carcinoma (HGSOC) molecular subtype (ProType), which encompasses 55 genes plus five housekeeping genes and is based on the NanoString platform.
June 17, 2020
2020 06 17 23 55 4085 Double Helix Strange Cancer Cell 400
At-home testing for genetic risk works for breast, ovarian cancers
By LabPulse.com staff writers
The findings were presented at the American Society of Clinical Oncology (ASCO) meeting, which was held May 29 to 31 in a virtual format.
May 31, 2020
2019 12 03 21 13 6201 Home Magnifying Glass 400
FDA clears Myriad's ovarian cancer test
By LabPulse.com staff writers
The clearance allows clinicians to use the test in women who are eligible for treatment with olaparib (Lynparza, Merck/AstraZeneca) in combination with bevacizumab (Avastin, Roche), the company said. Lynparza is a poly (ADP-ribose) polymerase (PARP) inhibitor developed by AstraZeneca and Merck; Myriad has been collaborating with AstraZeneca since 2007 to develop companion diagnostics for Lynparza, according to the firm.
May 10, 2020
2019 11 04 21 37 0904 Ovarian Cancer 400
CMS broadens coverage for NGS tests in breast, ovarian cancers
By LabPulse.com staff writers
In a decision memo issued January 27, CMS announced that it will be covering NGS tests that are cleared or approved by the U.S. Food and Drug Administration (FDA) for some patients. The agency explained that its coverage determination applies to patients who have breast or ovarian cancer, as long as the patient has a risk factor or clinical indication for germline (inherited) breast or ovarian cancer and has not been previously tested with the same test for the same germline genetic content.
January 26, 2020
2019 08 05 19 10 8249 Dollar Sign 400
Todos gains U.S. lab, Videssa cancer tests via Provista deal
By LabPulse.com staff writers
Provista has developed a line of protein-based blood tests for the early diagnosis of cancer. Its Videssa Breast blood test is commercially available for help in interpreting abnormal or difficult-to-interpret imaging findings. Tests based on the same technology are being developed for endometrial cancer, ovarian cancer, and cancers associated with HPV.
January 8, 2020
2020 01 09 22 46 7361 Business Deal Corporate 400
NCCN updates pathology guidance in ovarian cancer
By LabPulse.com staff writers
In the new version, released on November 26, the guidelines now read:
December 1, 2019
2019 12 02 21 08 0302 Uterus Pelvic 400
CA-125 blood test better than expected in ovarian cancer
By LabPulse.com staff writers
In the study of 50,780 women with symptoms of ovarian cancer such as bloating and abdominal pain, 6.8% had an abnormally high level of CA-125 -- defined as at least 35 U/mL. Of those with high levels, it turned out that 10% had ovarian cancer, the researchers shared in a poster presentation.
November 4, 2019
2019 11 04 21 37 0904 Ovarian Cancer 400
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