AI-driven app uses blood biomarkers to flag high-risk COVID-19 patients

By LabPulse.com staff writers

June 3, 2020 -- A new mobile app uses artificial intelligence (AI) to assess key biomarkers from blood tests and help clinicians identify patients who are most at-risk for developing more severe cases of COVID-19.

The app's development was led by researchers at the NYU College of Dentistry, who used data from 160 patients in Wuhan, China to identify four biomarkers in blood tests that were significantly elevated in patients who died from the novel coronavirus:

  • C-reactive protein (CRP)
  • Myoglobin (MYO)
  • Procalcitonin (PCT)
  • Cardiac troponin I (cTnI)

These biomarkers can signal complications, like acute inflammation, lower respiratory tract infection, and poor cardiovascular health. Researchers built a model using the biomarkers and risk factors, like age and sex, and trained a machine learning algorithm to define the patterns of COVID-19 disease and give patients a severity score. After biomarkers and risk factors are entered into the model, it produces a score from 0 (mild or moderate) to 100 (critical).

To make the tool available and convenient for clinicians, researchers developed a mobile app that can be used at the point of care to quickly calculate a patient's severity score. It has recently been tested and optimized at the Family Health Centers at NYU Langone in Brooklyn.

Development of and experience with the risk score model were described in an article on June 3 Lab on a Chip, a journal of the Royal Society of Chemistry. The plan is to roll the app out nationwide in the coming weeks.

Ultrasound autopsies help São Paulo doctors understand COVID-19
A hospital in São Paulo used a portable ultrasound machine to perform autopsies on 10 patients with fatal cases of COVID-19. The authors described...
Kaiser members get another reprieve on out-of-pocket COVID-19 fees
Kaiser Permanente announced it will extend its waiver for most member out-of-pocket costs for inpatient and outpatient services related to the treatment...
Confirm BioSciences secures EUA for COVID-19 antibody test
Confirm BioSciences has secured an emergency use authorization (EUA) from the U.S. Food and Drug Administration for its COVID-19 immunoglobulin G/immunoglobulin...
Gates Foundation funds smartphone diagnoses for Africa
Decision-support software company VisualDx has received a grant from the Bill & Melinda Gates Foundation to develop a decision-support tool that enables...
Smartphones double as point-of-care diagnostics
Smartphones are evolving into new point-of-care diagnostic tools, changing the way many common health conditions are diagnosed. Such devices can now compete...

Copyright © 2020 LabPulse.com

Last Updated ls 6/3/2020 1:43:31 PM



Subscribe Today
Do you want to be a Microbiology Insider?

When LabPulse gets hot new information, our Insiders are the first to find out. Stay current in today's competitive market by receiving our exclusive free email updates.

Yes, Keep Me Current