Science Advisory Board

Chromatography
Tech Overview: Color measurement technology
The most common application for color measurement instruments is the analysis of solid and printed materials. However, other suitable devices may also be used to analyze liquid, slurries, powders, and more. It is important to note that filter photometers measure concentration in liquid samples contained in cuvettes while colorimeters are specifically used for the analysis of the color of the sample itself. Such measurements are based upon a predetermined color standard that has been developed to model color as perceived by the human eye.
December 20, 2018
2019 01 04 21 18 2885 2019 01 03 18 45 8870 Article Fluorescence
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Biosimilars: How the FDA is boosting demand in analytical instrumentation
Instrument suppliers who are monitoring this development closely are asking questions that are difficult to pin down. Will there be an increased need for instrumentation or instrumentation features to meet the demand for biosimilar drugs? What types of new instruments or features will be required to determine biosimilarity? How will the types of molecules targeted influence decision-making regarding pipeline prioritization and analytical instrumentation selection?
December 18, 2018
2019 01 04 21 46 0788 2019 01 03 19 34 5551 Article Biosimilars
Spectroscopy
Tech Overview: Molecular spectroscopy
Molecular spectroscopy is the analysis of molecular species by measuring the interaction of light with a specific sample. The absorption, emission, and/or reflection from a sample of light with wavelengths in the ultraviolet, visible, and/or infrared regions is characteristic of the various molecular vibrations, rotations, and other changes in the energy states of the interacting chemical species, and are unique to different molecular species. Molecular spectroscopy techniques are generally nondestructive and broadly applicable. Ultraviolet/visible (UV/Vis), near-infrared (NIR), and infrared (IR) spectroscopy techniques typically measure the sample’s absorption of the particular portion of the light spectrum they probe. Fluorescence spectroscopy irradiates a sample, but instead of measuring the absorbed energy, it measures the wavelengths and power of the energy that is re-emitted from the sample due to the initial excitation irradiation. Raman spectroscopy measures the spectrum of light scattered from the molecules in a sample. Nuclear MR investigates the absorption of radiofrequency electromagnetic radiation due to interactions with the magnetic properties of the nuclei in the sample. Refractometry, ellipsometry, and color measurement investigate other ways in which samples interact with light.
December 11, 2018
2019 01 04 21 45 3905 2019 01 03 19 35 7314 Article Molspec
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