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Exploratory trial links kinase inhibitor to epigenetic changes in dementia patients
Results from a clinical trial show that a small molecule that binds to kinases involved in inflammatory signaling may induce epigenetic changes in people with mild cognitive impairment and probable Alzheimer’s disease.
August 22, 2023
AI system in development aims for earlier endometriosis diagnosis
IMAGENDO uses machine learning to digitally combine the diagnostic capabilities of pelvic scans and MRI to identify endometriosis lesions. The researchers are seeking to optimize and validate the algorithm.
August 21, 2023
Messenger RNA shows preclinical promise as in vivo gene editing treatment for sickle cell
The delivery of the editing system resulted in the near-complete correction of hematopoietic sickle cells. A preclinical test linked the approach to a 91.7% increase in functional hemoglobin and a significant fall in the number of sickled cells.
August 14, 2023
PacBio, GeneDx team up to test if long-read sequencing improves pediatric diagnoses
In the study, GeneDx, a genetic testing company, will use PacBio’s Revio sequencing system to perform WGS and analysis of samples from 350 people and their biological parents.
August 10, 2023
Quest Diagnostics launches consumer-initiated Alzheimer’s risk assessment test
The new test uses the same technology as Quest's clinical AD-Detect Amyloid Beta 42/40 Ratio biomarker test for assessing amyloid beta protein, a recognized marker for Alzheimer’s, which was made available for physicians in early 2022.
August 1, 2023
Cumulus Neuroscience partners with U.K. universities on cognition test for early Alzheimer’s diagnosis
The partnership will look to scale the development and testing of the Fastball EEG test, which uses an EEG headset to measure brain activity while patients watch a series of flashing images displayed on a tablet or smartphone screen.
July 25, 2023
Thermo Fisher launches first reproductive health assays on Ion Torrent sequencer
The products, the Ion ReproSeq PGT-A Kit and the Ion AmpliSeq Polyploidy Kit, are the first reproductive health assays available for the company’s Ion Torrent Genexus Integrated Sequencer.
July 21, 2023
Analysis of 462M lipid test results reveals global variation in cholesterol levels
Mean total cholesterol levels exceeded the World Health Organization (WHO) target in seven of the 17 countries included in the analysis, namely Japan, Australia, North Macedonia, Switzerland, Germany, Slovakia, and Austria.
July 17, 2023
Whole genome sequencing finds genetic disorders missed by targeted test in babies
WGS found a genetic disorder in 49% of the patients, compared to a 27% detection rate for NewbornDx. Overall, a molecular diagnostic variant was found in 51% of participants; 134 of the 297 identified variants were novel.
July 14, 2023
Epigenetic study links DNA methylation to diseases including breast cancer and diabetes
Through the analysis, the researchers identified 69 associations between CpGs and the prevalence of breast cancer, chronic kidney disease, ischemic heart disease, and type 2 diabetes. The majority of the associations had not previously been described.
July 12, 2023
DiamiR Biosciences partners with JADBio on diagnostic tests, validation for biomarker panels
Under the deal, DiamiR will apply the capabilities of JADBio’s Automated Machine Learning (AutoML) bioinformatics platform and services to its own microRNA platform.
July 12, 2023
Roche receives FDA clearance for test to accelerate diagnosis of Alzheimer’s
The new 510(k) clearance covers two tests that run on Roche’s Elecsys immunoassay system. One of the assays, which measures beta-amyloid, was part of the 510(k) clearance that Roche received last year.
June 29, 2023
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