32-year-old woman with a neck mass
History and images
Our appreciation is extended to Dr. Abdul Abid, University of Texas Medical Branch, for contributing this case.
History: A 32-year-old woman with history of cervical cancer and adjuvant radiation treatment presented with a neck mass. Ultrasound examination revealed a 3.2-cm right thyroid nodule. A positron emission tomography (PET) scan demonstrated a hypermetabolic right thyroid nodule. Fine-needle aspiration was attempted and cytology reported “atypia of undetermined significance.” The right lobe of the thyroid was excised and sent for histology. A cross section of the thyroid lobe and photomicrographs are provided.
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Papillary thyroid carcinoma
Hürthle cell neoplasm
Thyroglobulin, thyroid transcription factor-1 (TTF-1)
Cytokeratin, androgen receptors
Cytokeratin 5/6 (CK 5/6), PAX 8
None of the above