Joseph Constance[email protected]COVID-19Study of unfolding pandemic saw shift in symptoms, reductions in vaccines protectionAccording to the study, racial and sociodemographic disparities persisted in the third year of SARS-CoV-2 circulation and were present in rhinovirus infection.December 9, 2022Prostate CancerHigher PSA screening rates associated with less metastatic prostate cancerInvestigators undertook a retrospective cohort study of patients to determine whether facility-level variations in PSA screening rates could be associated with subsequent facility-level metastatic prostate cancer incidence.October 25, 2022SequencingUniversity of Pittsburgh NGS test shows high sensitivity in pancreatic cyst studyBy sequencing 22 pancreatic cyst-associated genes, the PancreaSeq test distinguished benign cysts from those that could become cancerous.October 6, 2022Immune System DiseasesCRISPR may enable rapid, sensitive test for COVID-19The device has the potential for use as a diagnostic test at the point of care (POC), according to its developers.September 26, 2022Coronary Artery DiseasePolygenic score predicts risk of sudden cardiac deathIn the study, published by researchers at Cedars-Sinai Medical Center in Los Angeles and collaborators elsewhere, patients with coronary artery disease but without severely impaired heart function received the highest polygenic risk score, indicating a 77% increased risk for sudden cardiac death.August 28, 2022ArrhythmiaIn study, genetic testing catches missed cardiac diagnosesResearchers at Northwestern University and colleagues reported that in their cohort study of 4,782 patients with a suspected genetic cardiomyopathy or arrhythmia, the combined testing approach captured nearly 11% of patients whose diagnosis would have been missed if genetic testing had been limited to a specific suspected disease.August 24, 2022Liver CancerBiomarker assay may speed primary liver cancer detectionWhile EVs are released by normal cells, they are released to a greater extent by tumor cells and cells within a tumor microenvironment. Investigators at the University of California at Los Angeles (UCLA) and collaborators elsewhere have developed a streamlined surface protein assay (HCC EV SPA) capable of analyzing and quantifying eight subpopulations of HCC EVs.August 15, 2022SequencingACP paper outlines position on genetic testingThe authors noted that tests for specific genetic variants, polygenic risk scores, multicancer early detection tests using cell-free DNA, and whole-genome sequencing are among the emerging approaches for testing.August 9, 2022COVID-19Researchers report on improved SARS-CoV-2 neutralization assayIn a study published recently in Nature Communications, the developers reported reconfiguring an earlier serological assay that they had developed based on a tri-part split-NanoLuc, a novel bioluminescence platform, to detect antibodies that bind to the SARS-CoV-2 spike protein.July 17, 2022InfectiousPharmacogenomic testing for better depression treatmentIn the study, the patients being treated for major depressive disorder (MDD) who received pharmacogenomics testing also experienced better depression outcomes soon after they were tested.July 13, 2022Page 1 of 6Next PageTop StoriesPCRQiagen partners with FBI on forensics assayQiagen has announced a collaboration with the FBI to develop a new assay to improve DNA quantification for use in forensics and human identification.ImmunoassaysUniversity of Florida researchers develop CRISPR-based assay for HPV detectionFDA ClearanceGeneoscopy receives FDA approval for CRC screening testLawsuitGerman court rules patent invalid in 10x infringement suit against NanoStringSponsor ContentVisit our Molecular Diagnostics Community
