Leica and Leap to partner on new DKK1 cancer assay

2020 04 14 17 10 6223 Test Tubes Rd Lab 20200414172749

Leica Biosystems and Leap Therapeutics plan to partner on a new cancer assay that will detect Dickkopf-related protein 1 (DKK1), with the goal of supporting new treatments for cancer.

The test will support clinical development of Leap's anti-DKK1 cancer therapy, DKN-01, which is currently in clinical trials. DKK1 is a protein often found in cancer that enables tumor cells to suppress the immune system; overexpression of it has been linked to poor survival in cancer patients, according to the two firms.

The new assay will use Bio-Techne RNAscope technology on Leica's Bond-III automated staining system, Leica and Leap said.

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