Man in his late forties with left renal mass    

Additional images and questions

What is the most likely diagnosis?
Renal angiomyoadenomatous tumor
Clear cell papillary renal cell carcinoma
Renal cell carcinoma with leiomyomatous stroma
Papillary renal cell carcinoma

What is/are the immunohistochemical staining positive marker(s)?
All of the above

What is AMACR a marker for?
Papillary renal cell carcinomas (RCCs), types 1 and 2
Mucinous RCCs
Tubular RCCs
Spindle RCCs
All of the above

What is the expected molecular FISH testing?
No loss of Chr 3p in renal cell carcinomas
Loss of Chr 3p in clear cell subtype
Both of the above

What is the prognosis?
Favorable prognosis with low rate of tumor recurrence
Poor prognosis and worse clinical course outcome