Cases
50-year-old man with painful solitary nodule   

Additional images and questions

Click images to enlarge.
Which genodermatosis is associated with this lesion?
Birt-Hogg-Dubé syndrome
Gorlin-Goltz syndrome
Cowden syndrome
Brooke-Spiegler syndrome

Which mutation is associated with this genodermatosis?
Conserved cylindromatosis (CYLD)
Folliculin gene (FLCN)
Alpha protein kinase 1 (ALPK1)
Protein patched homolog 1 (PTCH1)
A and C

Which other lesions are the most common in this genodermatosis?
Basal cell carcinomas and basaloid follicular hamartomas
Cylindromas and trichoepitheliomas
Perifollicular fibroma and trichodiscoma
Acral keratosis and mucocutaneous neuromas

The lesion frequently metastasizes.
True
False