Lab News
Tumor mutational burden biomarker may not pass muster (again) at ASCO
May 20, 2019 -- Foundation Medicine is set to present data supporting its cancer diagnostics and the tumor mutational burden biomarker at the American Society of Clinical Oncology (ASCO) meeting, set for May 31 to June 4.  Discuss
Single-cell sequencing supplies clues about managing lupus
May 20, 2019 -- Single-cell RNA sequencing (scRNA-seq) helped researchers identify a molecular signature associated with response to treatment for lupus nephritis in a study of renal and skin biopsies published May 20 in Nature Immunology.  Discuss
So far, so good with NCI pediatric molecular screening study
May 16, 2019 -- In a large molecular screening study sponsored by the U.S. National Cancer Institute (NCI), 24% of pediatric cancer patients were matched with targeted therapies based on genetic profiles from tumor samples, a better than expected result, investigators reported during an American Society of Clinical Oncology press briefing on May 15.  Discuss
Liquid biopsies show the way in melanoma and rectal cancer
May 16, 2019 -- The potential role for circulating tumor DNA in guiding treatment and monitoring response received more support from a pair of separate studies on rectal cancer and melanoma published May 15 in association with medical meetings.  Discuss
Babesiosis testing makes strides with FDA clearances
May 15, 2019 -- There have been some interesting developments in the IVD market, specifically in the area of tick-borne diseases. Tick-borne diseases beyond Lyme are getting attention due to a lack of reliable diagnostic tests, but that's starting to change for at least one disease, babesiosis, according to Bruce Carlson of Kalorama Information.  Discuss
T2Bacteria panel proves itself, but will hospitals buy in?
May 14, 2019 -- The T2Bacteria panel was accurate and fast for detecting five common kinds of bacteria in the blood in a multicenter study published May 13 in the Annals of Internal Medicine, but questions remain about its value in practice and how it would be incorporated into a hospital's workflow.  Discuss
AMP, CAP show labs what they need to include in CYP2C9 tests
May 13, 2019 -- Labs should be including a broad set of CYP2C9 alleles in their own genotype tests, according to new joint recommendations published May 7 by the Association for Molecular Pathology (AMP) and the College of American Pathologists (CAP) in the Journal of Molecular Diagnostics.  Discuss
Smaller labs eye digital pathology options to improve workflow
May 9, 2019 -- As workloads increase in laboratory medicine, some pathology labs have considered harnessing new technologies to improve workflow and efficiency. One of the most promising technologies is digital pathology -- but it carries a price.  Discuss
Failed study leaves CRP test hanging as biomarker in bipolar depression
May 8, 2019 -- Investigators tried and failed to use C-reactive protein (CRP) as an inflammatory biomarker for picking patients with bipolar depression for drug treatment in a small study published May 8 in JAMA Psychiatry.  Discuss
Computational technique deployed for tumor tissue analysis
May 7, 2019 -- Stanford University researchers outlined a digital cytometry computational method that is useful for characterizing individual cells in intact tumor tissue samples. The technique could possibly predict response to cancer immunotherapy, according to a May 6 report in Nature Biotechnology.  Discuss
Conferences
Digital MedTech Conference
May 22-23
San Francisco, California United States
Newark Workshops for Laboratory Professionals
May 29-31
Newark, New Jersey United States
Albuquerque Workshops for Laboratory Professionals
May 29-31
Albuquerque, New Mexico United States
American Society of Clinical Oncology (ASCO) Annual Meeting
May 31 - June 4
Chicago, Illinois United States
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