Maryam Payne

Malaria
Study shows malaria drug resistance occurring in Horn of Africa
Malaria parasites in eastern Africa have developed resistance to artemisinins, essential first-line drugs used in combination therapies, jeopardizing the progress made in recent decades against the disease.
September 29, 2023
Plasmodium Falciparum Malaria Cdc Social
Gene silencing and gene editing
CRISPR-Cas3 technique restores dystrophin function in iPSCs from DMD patients
Researchers have developed a dual CRISPR-Cas3 gene editing technique to restore dystrophin function in induced pluripotent stem cells (iPSCs) from patients with Duchenne muscular dystrophy (DMD).
August 24, 2023
This photo shows green dystrophin protein restored by dual-Cas3 in skeletal muscle derived from DMD patient iPSCs.
Gene expression
Castle Biosciences reports study validation for melanoma gene expression test
The study findings support results from a recently published study which showed that patients who received routine imaging guided by high-risk 31-GEP test scores had earlier diagnoses of recurrence, which in turn led to better outcomes for patients.
July 6, 2023
Pathology Slide Melanoma Social
Spectroscopy
Scanning ion conductance spectroscopy in study enables precise DNA identification
The scanning ion conductance spectroscopy system slows a molecule’s transit through a nanopore, allowing thousands of consecutive readings to be taken of the same molecule, as well as of different locations on the molecule.
June 21, 2023
Dna Sequence Social
Prostate Cancer
Bio-Techne announces interim results on prostate test long-term study
In the prospective, randomized study, researchers are assessing the clinical outcomes of 1,049 men ages 50 and over who have prostate specific antigen (PSA) in the gray zone of uncertain prostate cancer risk.
May 18, 2023
Cancer Cells Prostate Social
Diabetic Nephropathy
Renalytix announces review data on kidney disease risk assessment test
A review of the data underscored the effectiveness of KidneyIntelX in identifying patients at greatest risk of decline into kidney failure at the earlier stages, when progression can be slowed.
April 19, 2023
Kidneys Social
HIV
Roche, CDC expand partnership on HIV and TB support for healthcare systems in critical regions
The public-private partnership, named Lab Networks for Health, aims to improve HIV and TB detection, prevention, and treatment in countries that have been hit hardest by the two diseases.
February 28, 2023
Bacteria Mycobacterium Tuberculosis Social
Research and Development
MIT researchers record cellular memories through protein chains
The protein chains can be imaged using a microscope, revealing cellular “memories,” shedding light on processes such as gene expression, drug treatment response, and memory formation.
January 3, 2023
Protein Interaction Network Map Social
Cancer
Study reveals biomarkers associated with immune checkpoint inhibitor myocarditis
Myocarditis during cancer treatment with an immune checkpoint inhibitor (ICI) was associated with increased levels of three biomarkers implicated in skeletal muscle damage.
December 21, 2022
Immune Checkpoint Molecule Pd L1 Social
Alzheimer's
Blood test in study detects proteins fundamental to dementia before symptoms develop
The research team is working with scientists at AltPep, a University of Washington spinout company, to develop a soluble oligomer binding assay as a diagnostic test.
December 5, 2022
Amyloid Plaque Alzheimer Social
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Mergers & Acquisitions
$16.5B CDMO deal unhindered by role in broader pharma supply chain
Novo Holdings greenlighted by European Commission to take control of U.S.-based CDMO.
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Compliance and Regulation
Texas lab owner accused of $79M RPP fraud scheme
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FDA Warning Letter
FDA sounds bacteria alarms over CGMP violations in Maine
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Research and Development
Revvity broadens work in newborn testing for NHS England
Body composition in patients treated with Ozempic
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Body composition in patients treated with Ozempic
More in Home
$16.5B CDMO deal unhindered by role in broader pharma supply chain
By Liz Carey
Novo Holdings greenlighted by European Commission to take control of U.S.-based CDMO.
December 11, 2024
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Texas lab owner accused of $79M RPP fraud scheme
By LabPulse.com staff writers
The DOJ implicated a Texas clinical laboratory owner and operator in respiratory pathogen panel testing fraud scheme.
November 25, 2024
Handcuffs Gavel Social
FDA sounds bacteria alarms over CGMP violations in Maine
By Liz Carey
Tom's troubles highlight the importance of being inspection-ready.
November 21, 2024
Fda Logo V2 Social
Revvity broadens work in newborn testing for NHS England
By LabPulse.com staff writers
Revvity, formerly PerkinElmer, will expand its work with Genomics England to continue the Generation Project.
November 20, 2024
Baby Infant Mom Closeup Social
Roche gets CE Mark for ovarian cancer CDx test
By LabPulse.com staff writers
Roche has received the CE Mark under the European Union's In Vitro Diagnostic Regulation for its companion diagnostic (CDx) test, which is designed to aid in identifying ovarian cancer patients eligible for targeted treatment with Abbvie's Elahere.
November 19, 2024
Ovarian Cancer2 Social
AMP reviews pitfalls of NGS testing for SARS-CoV-2
By Liz Carey
Document offers key pre-analytical, analytical, and post-analytical considerations to help improve NGS-based surveillance programs.
November 15, 2024
Covid Treatment Doctor Social
FDA fall IVD roundtable avoids LDT questions
By Liz Carey
In addition, CAP LDT webinar offers beginning guide for phase one compliance.
November 12, 2024
Diagnostic Analyzer Lab Pcr Social
Lucy Letby murder case flags immunoassays as unreliable for medical evidence
By Liz Carey
At least one pathologist has said it was wrong for scientists representing Liverpool Clinical Laboratories to insist insulin poisoning was the only explanation in a series of high-profile newborn deaths in the U.K., The Telegraph reported.
October 28, 2024
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Digital pathology rollouts race for proof-of-concept at national level
By Liz Carey
U.K. invests in clinical trial security while Australia's health minister issues powerful ultimatum.
October 29, 2024
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Caris Life Sciences embarks on 10K-sample breast cancer biomarker analysis project
By LabPulse.com staff writers
Caris will perform comprehensive molecular characterization of TAILORx tissue samples.
October 25, 2024
Dna Sequence (1)
ASCLS seeks support for med lab personnel act
By LabPulse.com staff writers
The proposed legislation includes loan repayment provisions and requires $25 million in the first year.
October 25, 2024
Washington Dc Capitol
Pathology groups' antitrust legal fight heats up
By LabPulse.com staff writers
A lawsuit in which Iowa pathologists are suing their former colleagues is escalating, with one side accusing the other of attempting to maintain a monopoly at the expense of patients.
October 24, 2024
Lawsuit Social
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