David Grenache, PhD

Inflammation
Interleukin-6 testing grows rapidly, with limited evidence of utility
Cytokines are small proteins released by many different types of cells, including the white blood cells of the immune system. Cytokines help regulate the immune system's response to an infection and cause inflammation. The storm happens when the release of cytokines goes into an uncontrolled overdrive causing hyperinflammation which damages the body's organs. In the lungs, this inflammation causes fluid to accumulate in the airspaces which then leads to ARDS.
June 8, 2020
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COVID-19
Opening the magic box: Lab professionals reveal their value during COVID-19
The SARS-CoV-2 testing bottleneck -- though now slowly opening -- has dramatically underscored just how crucial diagnostic testing is to individual and public health. Not knowing quickly and accurately who has been infected with the virus has complicated care for patients suspected of having COVID-19 illness and hamstrung public health attempts to control and contain the virus's spread. This knowledge also will be crucial as the country grapples with reopening the economy.
April 19, 2020
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Top Stories
Kidney Social
Artificial Intelligence
AI model reveals kidney tumor features, potential for treatment response prediction
Researchers at the Dana-Farber Cancer Institute have trained artificial intelligence (AI) models to assess the clinical features of kidney cancer tumor samples to predict how tumors may respond to immune therapy.
Breast Cancer3 Social
Breast Cancer
Consumer genetic testing may misrepresent breast cancer risk: Study
Dna Genome Gene Targeted Social
Financing
Rome Therapeutics raises $72M in series B financing
Lab Scientists Social
Regulatory Guidance
NIH to require international collaborators to share all data
At-home or Lab-based STI testing/collection
Sponsor Content
At-home or Lab-based STI testing/collection
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AI model reveals kidney tumor features, potential for treatment response prediction
Researchers at the Dana-Farber Cancer Institute have trained artificial intelligence (AI) models to assess the clinical features of kidney cancer tumor samples to predict how tumors may respond to immune therapy.
September 22, 2023
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Consumer genetic testing may misrepresent breast cancer risk: Study
Women are being told they are at high risk of breast cancer from consumer genetic test results which do not take family history into account, say researchers.
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Rome Therapeutics raises $72M in series B financing
Biotech company Rome Therapeutics has raised a further $72 million in financing to develop medicines for autoimmune diseases and continue its exploration of the “dark genome.”
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NIH to require international collaborators to share all data
Despite concerns from researchers and organizations, the U.S. National Institutes of Health (NIH) will implement its new mandate requiring foreign partners to share raw data and notebooks at regular set intervals with their primary U.S. grant recipients.
September 22, 2023
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Many British health trusts slow to adopt electronic records systems, shows BMJ survey
Many health organizations in England are still reliant on paper patient notes and drug charts, despite progress toward electronic records and prescribing, The BMJ has found.
September 22, 2023
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Danaher cuts cost of rapid TB test after years of pressure from activists
Danaher has cut the cost of one of its tuberculosis (TB) tests in less developed countries after years of public pressure to lower the price.
September 21, 2023
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Protein biomarker may aid in early Parkinsonian disorders detection
A protein biomarker present in cerebrospinal fluid and blood plasma may be useful for the early diagnosis of Parkinsonian disorders.
September 21, 2023
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Day Zero Diagnostics completes $16M financing round
Day Zero Diagnostics has completed a $16 million financing round, executed as a convertible note.
September 20, 2023
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Polygenic risk scores from multi-ancestry GWASs more accurate in diverse groups: Study
Polygenic risk scores (PRS) derived from multi-ancestry genome-wide association studies (GWASs) outperform PRSs based on single-ancestry GWASs in underrepresented populations, new research shows.
September 21, 2023
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Researchers develop signature for scoring thyroid cancers
A team led by researchers at Vanderbilt University Medical Center has developed a signature for thyroid cancer aggressiveness that incorporates immune and other microenvironment features through multiomic analyses.
September 20, 2023
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NIH starts early-phase trial of second-generation universal flu vaccine candidate
The U.S. National Institutes of Health (NIH) has begun an early-phase clinical trial of its second-generation universal flu vaccine candidate.
September 20, 2023
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Broken String Biosciences raises $15M in series A financing round
Broken String Biosciences has closed a $15 million series A financing round.
September 19, 2023
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