Samantha Black, PhD

Gene silencing and gene editing
Bio-Techne launches multiplex spatial genomics assay
The RNAscope HiPlex V2 assay is designed to enable a deeper understanding of gene expression patterns at a single-cell resolution. The assay can generate precision expression data from 12 targets in FFPE samples and up to 48 targets in fresh and fixed frozen samples, according to the company.
July 26, 2021
2021 07 27 16 28 2741 2021 07 27 Rn Ascope Hi Pex V2 400
Lab Automation Software
Survey: Scientists want to boost use of lab automation
In total, 74% of scientists reported that less than half of their lab operations are automated. Of those surveyed, 19% of respondents said that their labs are between 51% and 75% automated and only 6% reported an automation percentage over 76%.
May 24, 2021
2021 05 26 03 31 8819 Automation Liquid Handling Titrator 400
Webinars
Preparation is key for postdocs to transition to industry positions
On-Demand Webinar -- Postdoctoral positions are a natural choice for many scientists who have just received their PhDs. Postdocs allow scientists to gain invaluable research experience and training under guided mentorship.
May 7, 2021
2021 05 07 18 10 3813 Natalia Screenshot 400
Webinars
How can women overcome challenges to success in life sciences?
April 16, 2021
2021 04 16 18 06 3428 Screenshot 2021 04 16 103002 400
Webinars
BioTools Innovator seeks to boost startups developing life science tools
April 9, 2021
2021 04 16 02 18 7540 2021 04 09 Bio Tools Zavala Screenshot 400
COVID-19
Detecting SARS-CoV-2 in blood may be early indicator of severe disease
With the original SARS-CoV virus, high serum viral load and detection of the virus at multiple sites were predictive of adverse clinical outcomes. With SARS-CoV-2, increased oropharyngeal (throat) viral loads have been associated with age. Disease severity has been suggested to be correlated to SARS-CoV-2 RNA detected in serum. The inability to control viral replication can lead to spread of infection to multiple organs, possibly causing severe disease and driving excessive inflammatory reactions.
September 1, 2020
2020 05 15 23 50 8470 2020 05 14 Bloodtest 400
Valley Fever
NIH establishes Centers for Research in Emerging Infectious Diseases
The focus of the global network will be investigations into how and where viruses and other pathogens emerge from wildlife and spill over to cause disease in people. The NIAID will provide approximately $82 million over five years to support the network.
August 26, 2020
2020 08 27 17 11 6347 Infectious Diseases Research 400
Influenza
Scientists urge surveillance of new SARS-CoV-2 variant
Coronaviruses have encoded proofreading mechanisms, unlike other pathogenic viruses, and as a result SARS-CoV-2 has very low sequence diversity. However, natural selection can result in favorable mutations that provide an advantage to viral infectivity or transmission. Antigenic single amino acid changes are observed in seasonal influenza viruses and in previous coronaviruses. For example, a single amino acid change in spike D480A/G in the receptor-binding domain of SARS-CoV became the dominant variant in the later stages of the 2003 to 2004 pandemic.
July 6, 2020
2020 06 17 20 35 0417 Covid 19 Antibody 400
COVID-19
Reverse genetics allows researchers to map SARS-CoV-2 in the body
The SARS-CoV-2 genome contains 16 nonstructural proteins, four structural proteins (spike, membrane, envelop, and nucleocapsid), and eight accessory proteins. The spike protein mediates viral entry by binding to the human angiotensin-converting enzyme 2 (ACE2) followed by proteolytic processing by TMPRSS2 and furin. Therefore, spike proteins are the main target of host neutralizing antibodies.
June 4, 2020
2020 06 03 22 00 3312 2020 06 02 Unc Sars Co V2 Ciliated 400
Common Cold
What we know about SARS-CoV-2 immunity so far
SARS-CoV-2, a novel coronavirus that emerged in 2019, is the seventh human coronavirus to be described. Four human coronaviruses circulate seasonally and cause common colds (alphacoronaviruses NL63 and 229E; betacoronaviruses HKU1 and OC43). Two other coronaviruses, SARS-CoV and MERS-CoV, have crossed from animal sources and have not become endemic.
May 25, 2020
2020 01 27 21 38 4451 Lab 2019 Coronavirus Test 400
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Influenza
CDC adds commercial lab contracts for infectious disease, bird flu testing
Clinical laboratories incentivized to develop diagnostic tests earlier.
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Regulatory Guidance
Multiregional clinical trial data on FDA watch for U.S. applicability
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Monkeypox
Seegene launches 3rd RUO mpox assay
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Policy and Regulation
Hospital labs targeted in proposed Calif. hospital licensing regulations
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CDC adds commercial lab contracts for infectious disease, bird flu testing
By Liz Carey
Clinical laboratories incentivized to develop diagnostic tests earlier.
September 17, 2024
Colorized transmission electron micrograph of avian influenza A H5N1 virus particles shown in yellow.
Multiregional clinical trial data on FDA watch for U.S. applicability
By LabPulse.com staff writers
Pivotal trials drawing on foreign clinical data in focus.
September 16, 2024
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Seegene launches 3rd RUO mpox assay
By LabPulse.com staff writers
After introducing two research use only (RUO) mpox assays in August, Seegene has expanded its mpox assay line with a third RUO assay designed to address the spread of the mpox virus variant clade Ib currently prevalent in the mpox outbreak in Africa.
September 10, 2024
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Hospital labs targeted in proposed Calif. hospital licensing regulations
By Liz Carey
Proposed changes could require some hospitals to materially alter their current operations, according to advisers.
September 11, 2024
Regulation Wheel Social
HudsonAlpha Institute gets $2.9M NIH grant for pediatric rare disease sequencing
By LabPulse.com staff writers
Scientists at the HudsonAlpha Institute for Biotechnology in Huntsville, AL, have been awarded a five-year, $2.9 million U.S. National Institutes of Health (NIH) grant to identify genetic contributors to rare diseases in children.
September 6, 2024
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ADLM releases guidance for blood lipid assessment, lipoprotein testing
By LabPulse.com staff writers
Document outlines recommendations for standardizing clinical lipid testing workflows.
September 4, 2024
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Seegene, Springer Nature launch PCR innovation program
By LabPulse.com staff writers
Molecular diagnostics firm Seegene and Springer Nature have launched a new project for the development of diagnostic assays, as part of their ongoing strategic partnership.
September 3, 2024
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European Court rules for Illumina in jurisdictional appeal
By LabPulse.com staff writers
The European Court of Justice ruled that the European Commission did not have jurisdiction over Illumina's acquisition of Grail, reversing a ruling by a lower court that dismissed Illumina's appeal and overturning a €432 million ($477.8 million) fine.
September 4, 2024
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BioMarin to lay off 225 employees, reorganize programs
By LabPulse.com staff writers
BioMarin Pharmaceutical will lay off 225 employees as part of a reorganization, according to a regulatory form the company filed with the U.S. Securities and Exchange Commission.
August 30, 2024
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CDC prioritizes mpox specimens for testing laboratories
By LabPulse.com staff writers
The CDC recommended that all laboratories performing mpox testing send certain types of clinical specimens to a laboratory that can perform clade-specific testing as quickly as possible.
August 28, 2024
Monkeypox Virus Social
University of Eastern Finland researchers develop algorithm for better breast cancer screening
By LabPulse.com staff writers
Researchers at the University of Eastern Finland have developed an algorithm to improve mammogram density assessment, with the potential to increase screening accuracy.
August 23, 2024
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FDA issues draft guidance for PCCPs for medical devices
By LabPulse.com staff writers
The U.S. Food and Drug Administration (FDA) has issued a draft guidance document for its proposed policies for predetermined change control plans (PCCPs) for medical devices.
August 23, 2024
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