Emily Hayes

COVID-19
What have labs learned from the COVID-19 pandemic?
It's not a matter of if but when the next global emergency happens, and there's a lot of room for improvement the next time around, using lessons learned from the experience with SARS-CoV-2 in 2020, advised Matthew Binnicker, PhD, director of clinical virology at the Mayo Clinic.
December 14, 2020
2020 01 27 21 38 4451 Lab 2019 Coronavirus Test 400
Alzheimer's
Tau Alzheimer's blood test gives PET a run for its money
The study of 490 people included healthy controls and participants with subjective cognitive decline or mild cognitive impairment who were tested for tau phosphorylated at threonine 217 (p-tau-217). Various methods of early detection of Alzheimer's were compared for their value in the detection of preclinical disease.
November 9, 2020
2020 11 10 18 38 4846 Elderly Patient Ambulatory 400
Inflammation
CRP changes are a 'very powerful' tool for COVID-19 triage
As a marker of inflammation, CRP testing has been of high interest for assessment of COVID-19, along with other lab measures. However, the new study focused on the change in CRP in the first few days of hospital admission as opposed to a single value when patients first arrived.
November 8, 2020
2020 11 09 18 07 5733 Doctor Nurse Ppe 400
510(k)
Top 10 LabPulse stories for 1st half of 2020
The most-viewed article for the first half was a story we ran in May about the U.S. Food and Drug Administration (FDA) publishing a list of commercial antibody tests for the novel coronavirus that should not be marketed due to failure to meet new regulatory requirements. While in the early days of the pandemic, the agency took a very lenient approach, allowing any developer to market an antibody test as long as it provided notification of intent to do so, the FDA later tightened its policies. Labs have been advised not to use tests that are on its removal list, which is continually updated, and to be sure to remove them from stock.
July 30, 2020
2019 12 19 23 07 2257 Top 10 Gold 400
Cervical Cancer
National cervical cancer screening guidelines shift to primary HPV testing
The ACS published a 2020 update to guidelines for cervical cancer screening for individuals at average risk in its publication CA: A Cancer Journal for Clinicians online July 30. Guidelines were last updated in 2012.
July 30, 2020
2020 07 29 23 56 6775 Hpv Infection 400
Alzheimer's
Tau blood test shows promise for very early Alzheimer's detection
One study was conducted at the lab of Dr. Randall Bateman, a Charles F. and Joanne Knight distinguished professor of neurology at Washington University in St. Louis. Researchers evaluated a mass spectrometry test for assessment of p-tau-217 and other tau fragments using small blood samples -- as small as 4 mL.
July 28, 2020
2020 07 29 20 05 8205 Biomarkers 400
Microbiology
LabPulse.com Microbiology Insider
Dear Microbiology Insider,
July 26, 2020
Point-of-Care Testing
Week in Review: Deep learning for prostate biopsies | National COVID-19 testing coordination at last? | C-reactive protein guides steroid therapy
Dear LabPulse Member,
July 23, 2020
Prostate Cancer
Google's deep learning outperforms general pathologists in prostate biopsies
The research comes from a deep-learning/artificial intelligence (AI) research team at Google Health in Palo Alto, CA. For the study, performance of the deep-learning system and general pathologists were compared to assessment by a panel of urologic subspecialist pathologists for the evaluation of prostate cancer needle core biopsy formalin-fixed paraffin-embedded (FFPE) specimens.
July 23, 2020
2020 07 22 21 31 9455 2020 07 23 Prostate Biopsy 400
Inflammation
CRP test guides steroid Rx for coronavirus, could help save lives
As an indicator of inflammation, CRP has been used in many different clinical scenarios, though its nonspecific nature is a downside. In this observational study, which was conducted at the Albert Einstein College of Medicine in the Bronx, New York, researchers analyzed efficacy and safety of systemic treatment with glucocorticoids -- an emerging and promising treatment option for coronavirus -- and how outcomes were associated with levels of CRP. Steroids are widely available as is the CRP lab test, they noted.
July 21, 2020
2019 06 03 17 30 1562 Lab Blood Tubes 400
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Top Stories
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Sepsis
Some emergency sepsis screening tools inadequate, EU study suggests
Two out of the four internationally recommended screening tools used by emergency medical services are inadequate for recognizing sepsis, say German researchers.
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HIV
HIV vaccine trial begins enrollment in U.S., South Africa
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Alzheimer's
Alzheimer’s drug approval poised to reshape APOE testing market
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Stock
Invitae receives noncompliance notice from NYSE
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Some emergency sepsis screening tools inadequate, EU study suggests
Two out of the four internationally recommended screening tools used by emergency medical services are inadequate for recognizing sepsis, say German researchers.
September 26, 2023
Sepsis Bacteria Social
HIV vaccine trial begins enrollment in U.S., South Africa
A clinical trial for a preventive HIV vaccine has begun enrollment in both the U.S. and South Africa.
September 25, 2023
Vial Vaccine Vial Tech Social
Alzheimer’s drug approval poised to reshape APOE testing market
The U.S. Food and Drug Administration (FDA) approval of Biogen and Eisai’s Alzheimer’s disease drug Leqembi is likely to drive changes in the APOE testing market, according to an article in GenomeWeb.
September 25, 2023
Amyloid Plaque Alzheimer Social
Invitae receives noncompliance notice from NYSE
San Francisco-based medical genetics company Invitae received a notice of noncompliance from the New York Stock Exchange (NYSE) on September 20 for its stock price closing under $1.00 per share for 30 consecutive days.
September 25, 2023
Business Graph Money Stocks Social
AI model reveals kidney tumor features, potential for treatment response prediction
Researchers at the Dana-Farber Cancer Institute have trained artificial intelligence (AI) models to assess the clinical features of kidney cancer tumor samples to predict how tumors may respond to immune therapy.
September 22, 2023
Kidney Social
Consumer genetic testing may misrepresent breast cancer risk: Study
Women are being told they are at high risk of breast cancer from consumer genetic test results which do not take family history into account, say researchers.
September 21, 2023
Breast Cancer3 Social
Rome Therapeutics raises $72M in series B financing
Biotech company Rome Therapeutics has raised a further $72 million in financing to develop medicines for autoimmune diseases and continue its exploration of the “dark genome.”
September 20, 2023
Dna Genome Gene Targeted Social
NIH to require international collaborators to share all data
Despite concerns from researchers and organizations, the U.S. National Institutes of Health (NIH) will implement its new mandate requiring foreign partners to share raw data and notebooks at regular set intervals with their primary U.S. grant recipients.
September 22, 2023
Lab Scientists Social
Many British health trusts slow to adopt electronic records systems, shows BMJ survey
Many health organizations in England are still reliant on paper patient notes and drug charts, despite progress toward electronic records and prescribing, The BMJ has found.
September 22, 2023
Doctor Fills Patient Medical Record Social
Danaher cuts cost of rapid TB test after years of pressure from activists
Danaher has cut the cost of one of its tuberculosis (TB) tests in less developed countries after years of public pressure to lower the price.
September 21, 2023
Bacteria Mycobacterium Tuberculosis Social
Protein biomarker may aid in early Parkinsonian disorders detection
A protein biomarker present in cerebrospinal fluid and blood plasma may be useful for the early diagnosis of Parkinsonian disorders.
September 21, 2023
Parkinsons Lewy Bodies Social
Day Zero Diagnostics completes $16M financing round
Day Zero Diagnostics has completed a $16 million financing round, executed as a convertible note.
September 20, 2023
Research Money Social
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