Research & Development
Dementia: Page 2
Cerebrospinal fluid test helps pinpoint dementia disorders
The meta-analysis of studies involving about 10,000 people with neurological disorders showed that neurofilament light protein as measured with a commercially available immunoassay was elevated for people with neurological and psychiatric conditions. Results were broadly similar; however, frontotemporal dementia and HIV-related cognitive decline were differentiated from other dementias, and Parkinson's disease was differentiated from atypical parkinsonian conditions.
June 17, 2019
High cholesterol offers clues in early-onset Alzheimer's disease
The study of 2,125 people, including those with early-onset Alzheimer's disease and controls, found higher mean low-density lipoprotein cholesterol (LDL-C) in a subset of patients with early-onset disease, a type of dementia that strikes before the age of 65.
May 29, 2019
Newly defined dementia disease | Blood-based biomarker for CJD | Metabolic pathway screening in children
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May 6, 2019
NIH study outlines pathology of newly defined dementia disorder
Called limbic-predominant age-related TDP-43 encephalopathy (LATE), the condition is characterized by misfolded TDP-43, a protein involved in the regulation of gene expression in the brain, and is associated with a decline in cognitive function.
April 29, 2019
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