Coronary Artery Disease

Elevated lipoprotein(a) predicts recurrent heart disease in seniors

Elevated lipoprotein(a), a bad cholesterol variant, was found to increase the risk of recurrent coronary heart disease in senior citizens.

June 13, 2023

RNA biomarkers may help confirm heart disease, study finds

RNA analysis of blood from patients with angiographically confirmed coronary artery disease demonstrates how RNA biomarkers may help confirm heart disease.

March 30, 2023

Clinical-grade wearables developer Cardiosense raises $15.1M in Series A financing

The Chicago-based digital health company is leveraging artificial intelligence and multisensor devices to develop tools that enable the early detection of cardiovascular disease.

December 8, 2022

Epigenetics testing firm Cardio Diagnostics goes public on Nasdaq

At the core of its cardiovascular solutions is the Integrated Genetic-Epigenetic Engine, developed at the University of Iowa.

October 26, 2022

Boston Heart Diagnostics launches polygenic risk map

The risk map leverages polygenic risk scores (PRS) to provide physicians with an understanding of a patient's absolute genetic risk of complex disease, allowing for the creation of early, personalized intervention strategies, the firm said.

September 12, 2022

Polygenic score predicts risk of sudden cardiac death

In the study, published by researchers at Cedars-Sinai Medical Center in Los Angeles and collaborators elsewhere, patients with coronary artery disease but without severely impaired heart function received the highest polygenic risk score, indicating a 77% increased risk for sudden cardiac death.

August 28, 2022

Clinics begin adopting Genetic Technologies risk test

The clinics can focus on testing for a single disease or multiple diseases, including breast cancer, colorectal cancer, ovarian cancer, coronary artery disease, prostate cancer, and type 2 diabetes, the company said.

June 30, 2022

Study identifies risk factors for death from coronavirus

In the observational study, Dr. Bin Cao of Capital Medical University and colleagues from China examined the data of 191 patients with confirmed COVID-19 at two different hospitals. The median age of the patients was 56 and nearly 30% died in the hospitals. They also had various comorbidities, the most common being hypertension (30% of patients), diabetes (19%), and coronary artery disease (8%).

March 10, 2020

Genetic risk scoring not ready for prime time in heart disease

One study evaluated risk scoring in a cohort of participants in UK Biobank, a nonprofit research project that is performing whole genome sequencing on a mass scale in the U.K. The observational study assessed polygenic risk scores, pooled cohort equations (risk prediction models), and both combined for predicting events in 352,660 participants with no cardiovascular disease at baseline.

February 18, 2020

Should blood donations be screened for high cholesterol?

Familial hypercholesterolemia is found in 1 in 250 individuals in the general population, and it can lead to premature coronary artery disease (CAD) due to elevated levels of low-density lipoprotein (LDL) cholesterol. The condition is underdiagnosed and undertreated, although it is easily detected through blood lipid profiles or genetic testing; treatment includes statins, which effectively reduce LDL cholesterol levels.

May 22, 2019

Gencove scores NIH small business grant

The amount of the grant was not disclosed.

April 25, 2019

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