Case Western Reserve University (CWRU) and partners were awarded a $3.3 million grant to evaluate the use of artificial intelligence (AI) for predicting treatment for patients with oral squamous cell carcinoma.
The U.S. National Cancer Institute awarded the five-year grant to a group led by Anant Madabhushi, PhD, the Donnell Institute Professor of Biomedical Engineering at CWRU and head of the Center for Computational Imaging and Personalized Diagnostics, and Dr. James Lewis Jr., a pathology, microbiology, and immunology professor at Vanderbilt University Medical Center.
The group will use advanced computer vision and machine-learning techniques to identify cancer and immune cells on digitized images of oral squamous cell carcinoma tissue slides and then recognize spatial patterns among those cells. The aim is for the AI algorithms to help oncologists and pathologists better determine which cancers are more aggressive, aiding their ability to determine whether patients need chemotherapy, radiation, or surgery.
The research will include other institutions such as the Cleveland Clinic and University Hospitals in Cleveland, the San Francisco Veterans Affairs (VA) Health System, and Tata Memorial Centre in Mumbai, India.