Nikon debuts artificial intelligence-assisted confocal microscopes

2021 04 27 21 25 3318 2021 04 27 Nikon Mouse Muscle 400

Nikon has released its next-generation confocal microscope series, including the AX and AX R. The microscopes feature a redesigned scan head with 8192 x 8192-pixel resolution, ultrahigh-speed resonant scanning, and a 25-mm field-of-view.

Nikon developed the microscope series to meet the demands for high resolution (both spatially and temporally) for a larger range of specimens and with greater throughput capabilities. Biological research is moving toward systems-level studies that include molecules to whole-cell populations, tissues, organoids, and even whole organisms.

A mouse muscle and neuromuscular junction imaged with a 25X silicone-immersion objective lens using 2048 x 2048-pixel resonant scanning and rendered and segmented using new 3D tools from NIS-Elements. Image courtesy of Nikon.A mouse muscle and neuromuscular junction imaged with a 25X silicone-immersion objective lens using 2048 x 2048-pixel resonant scanning and rendered and segmented using new 3D tools from NIS-Elements. Image courtesy of Nikon.

The microscopes are equipped with NIS-Elements C imaging software and a suite of artificial intelligence-based tools that assist users in acquisition, processing, and analysis.

The company also said that users of the AX R's high-speed resonant scanner can acquire up to 720 frames per second (fps) at 2048 x 16 pixels. High-speed resonant scanning enables dynamic events to be easily captured, while also reducing the amount of time required to image large, fixed specimens, Nikon said.

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